def doLayout(self):
    sizer = wx.BoxSizer(wx.HORIZONTAL)		

    btn1 = wx.Button (self, wx.NewId(), "Button 1")
    btn2 = wx.Button (self, wx.NewId(), "Button 2")

    sizer.Add (btn1, flag = wx.TOP, border = 8)
    sizer.Add (btn2, flag = wx.ALL, border = 8)

    self.SetSizer(sizer)
    self.Layout()