def doLayout(self):
    staticbox0 = wx.StaticBox (self, wx.NewId(), label="StaticBox 0")
    sizer_vert = wx.StaticBoxSizer(staticbox0, wx.VERTICAL)

    staticbox1 = wx.StaticBox (self, wx.NewId(), label="StaticBox 1")
    staticbox2 = wx.StaticBox (self, wx.NewId(), label="StaticBox 2")

    sizer_1 = wx.StaticBoxSizer(staticbox1, wx.HORIZONTAL)
    sizer_2 = wx.StaticBoxSizer(staticbox2, wx.VERTICAL)

    sizer_vert.Add (sizer_1)
    sizer_vert.Add (sizer_2, flag = wx.ALIGN_RIGHT | wx.ALIGN_BOTTOM)

    btn1 = wx.Button (self, wx.NewId(), "Button 1")
    btn2 = wx.Button (self, wx.NewId(), "Button 2")
    btn3 = wx.Button (self, wx.NewId(), "Button 3")
    btn4 = wx.Button (self, wx.NewId(), "Button 4")

    sizer_1.Add (btn1)
    sizer_1.Add (btn2)

    sizer_2.Add (btn3)
    sizer_2.Add (btn4)